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Bisindolylmaleimide VIII acetate
CAS No. 138516-31-1
Bisindolylmaleimide VIII acetate ( Ro 31-7549 acetate; Bis VIII acetate )
Catalog No. M23542 CAS No. 138516-31-1
Bisindolylmaleimide VIII acetate is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 141 | In Stock |
|
| 10MG | 224 | In Stock |
|
| 25MG | 471 | In Stock |
|
| 50MG | 683 | In Stock |
|
| 100MG | 954 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBisindolylmaleimide VIII acetate
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NoteResearch use only, not for human use.
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Brief DescriptionBisindolylmaleimide VIII acetate is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC).
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DescriptionBisindolylmaleimide VIII acetate is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC). It has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively.
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SynonymsRo 31-7549 acetate; Bis VIII acetate
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis;PKC;PKCα;PKCβ1;PKCβ2;PKCγ;PKCε
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Research Area——
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Indication——
Chemical Information
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CAS Number138516-31-1
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Formula Weight458.5
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Molecular FormulaC26H26N4O4
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C(C1=CN(CCCN)C2=C1C=CC=C2)=C3C4=CN(C)C5=C4C=CC=C5)NC3=O.CC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wilkinson SE, et al. Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. Biochem J. 1993 Sep 1;294 ( Pt 2):335-7.
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